The increase in opioid overdose deaths has created an urgency for medical examiners/coroners (ME/Cs) to identify and connect to other sources of information or data that can assist them in completing their investigations more accurately and efficiently. A data source that ME/Cs have identified as a valuable tool in carrying out their roles is the PDMP. An increasing number of ME/Cs use decedents’ PDMP data to assist in determining whether and to what extent prescription drugs caused or contributed to an individual’s death.